Stefano Manfredini Selected Research

Neoplasms (Cancer)

6/2022	Synthesis and Biological Evaluation of Highly Active 7-Anilino Triazolopyrimidines as Potent Antimicrotubule Agents.
3/2021	A facile synthesis of diaryl pyrroles led to the discovery of potent colchicine site antimitotic agents.
8/2020	Design, synthesis, in vitro and in vivo biological evaluation of 2-amino-3-aroylbenzo[b]furan derivatives as highly potent tubulin polymerization inhibitors.
5/2020	Synthesis and Biological Evaluation of 2-Substituted Benzyl-/Phenylethylamino-4-amino-5-aroylthiazoles as Apoptosis-Inducing Anticancer Agents.
4/2020	Synthesis and Biological Evaluation of New Antitubulin Agents Containing 2-(3',4',5'-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold.
6/2018	Hyaluronic Acid in the Third Millennium.
2/2007	Nidogen 1 and 2 gene promoters are aberrantly methylated in human gastrointestinal cancer.

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Stefano Manfredini Research Topics

Disease

7	Neoplasms (Cancer) 06/2022 - 02/2007
6	Melanoma (Melanoma, Malignant) 09/2020 - 03/2018
3	Friedreich Ataxia (Friedreich's Ataxia) 01/2020 - 08/2007
2	Infections 03/2019 - 01/2004
2	Acute Erythroblastic Leukemia (Erythroleukemia) 01/2019 - 08/2018
2	Dermatomycoses 09/2016 - 06/2015
2	Alzheimer Disease (Alzheimer's Disease) 12/2015 - 12/2014
2	Inflammation (Inflammations) 01/2015 - 08/2011
2	Atherosclerosis 06/2007 - 12/2006
2	Chronic Disease (Chronic Diseases) 07/2006 - 12/2002
1	Hyperpigmentation 03/2022
1	Plague (Bubonic Plague) 04/2020
1	Skin Neoplasms (Skin Cancer) 12/2019
1	Gonorrhea 06/2019
1	Poisoning 01/2019
1	Psoriasis (Pustulosis Palmaris et Plantaris) 10/2018
1	Lung Diseases (Lung Disease) 07/2018
1	Yellow Fever 01/2018
1	Communicable Diseases (Infectious Diseases) 01/2018
1	Dengue (Dengue Fever) 01/2018
1	Zika Virus Infection 01/2018
1	Carcinogenesis 10/2016
1	Sunburn 10/2016
1	T-Cell Leukemia (Leukemia, T Cell) 04/2016
1	Leukemia L1210 04/2016
1	Carcinoma (Carcinomatosis) 04/2016
1	Cystic Fibrosis (Mucoviscidosis) 01/2013
1	Thrombosis (Thrombus) 08/2012
1	Mitochondrial Diseases (Mitochondrial Disease) 11/2010
1	Diarrhea 04/2008
1	Heart Diseases (Heart Disease) 06/2007

Drug/Important Bio-Agent (IBA)

6	AntioxidantsIBA 04/2020 - 12/2004
3	TubulinIBA 06/2022 - 04/2020
3	Pharmaceutical PreparationsIBA 09/2016 - 08/2011
3	FeAOX-6IBA 06/2007 - 12/2004
2	fosbretabulin (combretastatin A4)IBA 03/2021 - 08/2020
2	PyrrolesIBA 03/2021 - 09/2020
2	HydrazonesIBA 01/2019 - 08/2018
2	Fluconazole (Zonal)FDA LinkGeneric 09/2016 - 06/2015
2	MetalsIBA 12/2015 - 12/2014
2	Amyloid (Amyloid Fibrils)IBA 12/2015 - 12/2014
2	Glycine (Aminoacetic Acid)FDA LinkGeneric 06/2015 - 05/2005
2	Reactive Oxygen Species (Oxygen Radicals)IBA 11/2010 - 07/2006
1	Aniline CompoundsIBA 06/2022
1	pyrimidineIBA 06/2022
1	Monophenol Monooxygenase (Tyrosinase)IBA 03/2022
1	PalladiumIBA 03/2021
1	benzimidazoleIBA 09/2020
1	Phosphates (Orthophosphate)IBA 08/2020
1	Cyclin-Dependent Kinases (cdk Proteins)IBA 05/2020
1	Antineoplastic Agents (Antineoplastics)IBA 05/2020
1	ThiazolesIBA 05/2020
1	poly(tetramethylene succinate-co-tetramethylene adipate)IBA 04/2020
1	ThiophenesIBA 04/2020
1	pyridineIBA 04/2020
1	SaltsIBA 04/2020
1	BenzimidazolesIBA 01/2020
1	TocotrienolsIBA 01/2020
1	Sunscreening Agents (Sunscreens)IBA 12/2019
1	VaccinesIBA 06/2019
1	Cephalosporins (Cephalosporin Antibiotics)IBA 06/2019
1	oleandrinIBA 01/2019
1	Hyaluronic Acid (Hyaluronan)IBA 07/2018
1	Urea (Carbamide)FDA LinkGeneric 07/2018
1	Biological ProductsIBA 07/2018
1	ascorbate-2-phosphateIBA 07/2018
1	CosmeticsIBA 06/2018
1	Insect RepellentsIBA 01/2018
1	DNA (Deoxyribonucleic Acid)IBA 10/2016
1	imidazoleIBA 04/2016
1	Cytostatic AgentsIBA 04/2016
1	IonsIBA 12/2015
1	Niacinamide (Nicotinamide)FDA LinkGeneric 06/2015
1	ArbutinIBA 06/2015
1	bisabolol (levomenol)IBA 06/2015
1	Glutathione (Reduced Glutathione)IBA 06/2015
1	azelaic acid (Azelex)FDA Link 06/2015
1	kojic acidIBA 06/2015
1	hydroquinone (Esoterica)FDA Link 06/2015
1	Rutin (Rutoside)IBA 01/2015
1	Hormones (Hormone)IBA 01/2015
1	FrataxinIBA 01/2013
1	Mitochondrial Proteins (Mitochondrial Protein)IBA 01/2013
1	WastewaterIBA 01/2013
1	IronIBA 01/2013
1	Interleukin-8 (Interleukin 8)IBA 01/2013
1	ChemokinesIBA 01/2013
1	Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA 08/2012
1	Suppositories (Vaginal Suppositories)IBA 08/2011
1	acteosideIBA 08/2011
1	RNA-Dependent RNA Polymerase (RNA Dependent RNA Polymerase)IBA 04/2008
1	NucleosidesIBA 04/2008
1	EnzymesIBA 04/2008
1	Vitamin E FDA LinkGeneric 08/2007
1	Fe-Aox29IBA 08/2007
1	idebenoneIBA 08/2007
1	alpha tocotrienolIBA 06/2007

Therapy/Procedure

3	Therapeutics 06/2019 - 01/2015
1	Joint Prosthesis 03/2019
1	Catheters 03/2019